Effects of Bladder Training and/or Tolterodine in Female Patients with Overactive Bladder Syndrome: A Prospective, Randomized Study
Journal of Korean Medical Science
;
: 1060-1063, 2006.
Artículo
en Inglés
| WPRIM
| ID: wpr-174101
ABSTRACT
We compared the effects of bladder training and/or tolterodine as first line treatment in female patients with overactive bladder (OAB). One hundred and thirty-nine female patients with OAB were randomized to treatment with bladder training (BT), tolterodine (To, 2 mg twice daily) or both (Co) for 12 weeks. Treatment efficacy was measured by micturition diary, urgency scores and patients' subjective assessment of their bladder condition. Mean frequency and nocturia significantly decreased in all treatment groups, declining 25.9% and 56.1%, respectively, in the BT group; 30.2% and 65.4%, respectively, in the To group; and 33.5% and 66.3%, respectively in the Co group (p<0.05 for each). The decrease in frequency was significantly greater in the Co group than in the BT group (p<0.05). Mean urgency score decreased by 44.8%, 62.2% and 60.2% in the BT, To, and Co groups, respectively, and the improvement was significantly greater in the To and Co groups than in the BT group (p<0.05 for each). Although BT, To and their combination were all effective in controlling OAB symptoms, combination therapy was more effective than either method alone. Tolterodine alone may be instituted as a first-line therapy, but may be more effective when combined with bladder training.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenilpropanolamina
/
Control de Esfínteres
/
Terapia Conductista
/
Compuestos de Bencidrilo
/
Resultado del Tratamiento
/
Evaluación de Resultado en la Atención de Salud
/
Terapia Combinada
/
Antagonistas Muscarínicos
/
Cresoles
/
Vejiga Urinaria Hiperactiva
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2006
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS