Double primary lung adenocarcinoma diagnosed by epidermal growth factor receptor mutation status / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 270-274, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-174339
ABSTRACT
A nodular density was detected on a chest radiograph taken from a 57-year-old Korean woman who was visiting a hospital for a routine check. Chest computed tomography revealed a 4.8 cm lobulated mass in the right lung and another focal nodular lesion in the left lung; biopsies of both lungs revealed adenocarcinoma. We conducted DNA sequencing and peptide nucleic acid clamping to investigate the potential double primary lung cancer. The results verified that the mass in the right lung had a mutation in the epidermal growth factor receptor, whereas the nodule in the left lung had a wild-type sequence, showing that these two were genetically different cancers from one another. Thus, we demonstrate that genetic testing is useful in determining double primary lung cancer, and we herein report on this case.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tórax
/
Biopsia
/
Radiografía Torácica
/
Adenocarcinoma
/
Pruebas Genéticas
/
Análisis de Secuencia de ADN
/
Constricción
/
Diagnóstico Diferencial
/
Factor de Crecimiento Epidérmico
/
Receptores ErbB
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Yeungnam University Journal of Medicine
Año:
2017
Tipo del documento:
Artículo
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