Insulin Resistance Changes after Metabolic/Bariatric Surgery

ABSTRACT

The concept of bariatric surgery, which was intended to lose weight, has turned into metabolic surgery. These changes were due to the fact that the resolution of diabetes and metabolic diseases after weight loss surgery were not associated with weight loss. The key pathogenesis of type 2 diabetes is explained by increased insulin resistance and reduced insulin secretion. Therefore, postoperative resolution of diabetes can be explained by improvement of insulin secretion or insulin resistance. It is known that the improvement of insulin secretion after surgery depends on the degree of preservation of preoperative beta cell function. In this study, the method of measuring insulin resistance is concretely summarized, and the improvement of diabetes after metabolic obesity surgery is focused on the improvement of insulin resistance.