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A Case about Use of Mycophenolate Mofetil in Acute Renal Failure Associated with Lupus Nephritis / 대한신장학회잡지
Korean Journal of Nephrology ; : 635-639, 2006.
Artículo en Coreano | WPRIM | ID: wpr-176125
ABSTRACT
Mycophenolate mofetil (MMF) is a immunosuppressive agent increasingly used in organ transplantation and autoimmune disease. We report a case about use of MMF in SLE patient with rapidly worsening renal function. A 24-year old female was admitted due to 1-week history of generalized edema. Despite use of diuretics and conventional supported care, generalized edema was more aggravated and serum creatinine was elevated up to 5.2 mg/dL. Ten days after the initial admission, we started hemodialysis. After hemodialysis, improvement of generalized edema was achieved. Eighteen days after initial hemodialysis, we started corticosteroids and MMF because she shows persistent heavy proteinuria and oliguria. After use of corticosteroids and MMF, clinical improvement of renal complication was achieved in this patient. About 6 weeks later, we could discontinue hemodialysis. On two year follow up duration, she shows good renal function and no evidence of lupus flare-up signs. We suggest MMF is one of therapeutic options for patients with severe lupus nephritis, especially those refractory or intolerant to conventional cytotoxic agents.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Oliguria / Proteinuria / Enfermedades Autoinmunes / Nefritis Lúpica / Estudios de Seguimiento / Trasplante de Órganos / Diálisis Renal / Corticoesteroides / Trasplantes / Creatinina Tipo de estudio: Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Nephrology Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Oliguria / Proteinuria / Enfermedades Autoinmunes / Nefritis Lúpica / Estudios de Seguimiento / Trasplante de Órganos / Diálisis Renal / Corticoesteroides / Trasplantes / Creatinina Tipo de estudio: Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Nephrology Año: 2006 Tipo del documento: Artículo