Comparison of Drug-Eluting Stent and Bare Metal Stent in Reducing Adverse Cardiac Event after Coronary Stenting in Hemodialysis Patients / 대한신장학회지
Korean Journal of Nephrology
;
: 73-81, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-177188
ABSTRACT
PURPOSE:
The patients treated with hemodialysis have been known to have a high 1-year mortality rate after percutaneous coronary intervention (PCI). We evaluated the clinical benefits of drug-eluting stent (DES), compared to bare-metal stent (BMS) in Korean hemodialysis patients.METHODS:
We studied 72 hemodialysis patients (MF=4923, age 60+/-11 years) treated with percutaneous coronary intervention (PCI) from January, 1999 to February, 2006. Forty four patients (MF=28 16, age 60+/-11 years) treated with DES and 28 patients (MF=217, age 60+/-12 years) with BMS were enrolled. A composite of major adverse cardiac and cerebral endpoints (MACCE) was defined as all-cause death, myocardial infarction, stroke, and target-vessel revascularization (TVR). We compared the incidence of MACCE between DES and BMS group.RESULTS:
A composite of MACCE occurred in none in DES group (n=44) and 4 in BMS group (n=28) within 3 months after coronary stenting (Kaplan-Meier survivalanalysis:
0% vs 14%, respectively, p= 0.02). After 3 months, there was no difference in the incidence of primary end points between two groups. Multi-vessel disease (OR 2.47, 95% CI 1.02-6.11, p<0.05) was associated with a significant increase in the incidence of MACCE within 18 months after coronary artery stentingCONCLUSION:
DES may be superior to BMS in reducing adverse cardiac outcome at early period after coronary stenting in HD patients. However, this study showed no significant difference with the lapse of time.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedad de la Arteria Coronaria
/
Stents
/
Incidencia
/
Diálisis Renal
/
Vasos Coronarios
/
Accidente Cerebrovascular
/
Stents Liberadores de Fármacos
/
Intervención Coronaria Percutánea
/
Infarto del Miocardio
Tipo de estudio:
Estudio de incidencia
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Nephrology
Año:
2010
Tipo del documento:
Artículo
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