Serum biomarkers for predicting pregnancy outcome in women undergoing IVF: human chorionic gonadotropin, progesterone, and inhibin A level at 11 days post-ET / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 28-32, 2012.
Article
en En
| WPRIM
| ID: wpr-17760
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE: This study was performed to assess the prognostic value of serum hCG, progesterone, and inhibin A levels measured at 11 days post-ET for predicting pregnancy outcome in women participating in IVF. METHODS: Between May 2005 and April 2008, sera were obtained from 70 infertile women who underwent IVF-ET at 11 days post-ET and stored. HCG, progesterone, and inhibin A levels were measured by commercial enzyme-linked immunosorbent assay kits. The predictive accuracy of hCG, progesterone, and inhibin A levels for establishment of intrauterine pregnancy and ongoing pregnancy was calculated by receiver-operating characteristic curve analysis. RESULTS: For the prediction of intrauterine and ongoing pregnancy, serum hCG was better than progesterone and inhibin A. The predictive performance of progesterone and inhibin A was similar. The serum progesterone and inhibin A levels were significantly correlated each other (r=0.915, p=0.010). CONCLUSION: A single measurement of the serum hCG level is sufficient to predict pregnancy outcome in IVF-ET patients.
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Índice:
WPRIM
Asunto principal:
Progesterona
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Ensayo de Inmunoadsorción Enzimática
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Resultado del Embarazo
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Biomarcadores
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Fertilización In Vitro
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Transferencia de Embrión
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Gonadotropina Coriónica
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Inhibinas
Tipo de estudio:
Prognostic_studies
Límite:
Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Clinical and Experimental Reproductive Medicine
Año:
2012
Tipo del documento:
Article