A Case of Multiple Myeloma with Biclonal (IgG-K and IgA-K) M-proteins / 대한임상병리학회지
Korean Journal of Clinical Pathology
;
: 310-314, 1998.
Artículo
en Coreano
| WPRIM
| ID: wpr-177889
ABSTRACT
Two M-protein peaks in serum protein electrophoresis are rarely present in patients with plasma cell discrasia. We describe a 72-year-old male patient with multiple myeloma secreting biclonal M-proteins, which were confirmed by immunofixation. Immunoelectrophoresis has some difficulties to dectect M components when a very small amount of M-protein develops an equivocally abnormal precipitation arc. In this case, serum protein electrophoresis revealed two M peaks, one in beta and the other in gamma globulin region. An immunoelectrophoresis revealed unequivocally abnormal precipitation arcs in IgA and K light chain regions, but the arc in IgG region was equivocal. We performed an immunofixation and confirmed biclonal gammopathy, IgA-K and IgG-K types. This result supports the view that immunofixation is an useful confirmatory test when immunoelectrophoresis results are equivocal.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Plasmáticas
/
Gammaglobulinas
/
Inmunoglobulina A
/
Inmunoglobulina G
/
Proteínas de Mieloma
/
Inmunoelectroforesis
/
Electroforesis
/
Mieloma Múltiple
Límite:
Anciano
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Clinical Pathology
Año:
1998
Tipo del documento:
Artículo
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