Nucleic Acid Recognition and Signaling by Toll-like Receptor 9: Compartment-dependent Regulation
Journal of Bacteriology and Virology
;
: 131-132, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-177893
ABSTRACT
Toll-like receptor 9 binds to DNA from bacteria or viruses and activates a signaling pathway that leads to the induction of proinflammatory cytokines and type I interferon. Adaptor complex AP-3 was required for TLR9 trafficking and the production of type I interferon but not for proinflammatory cytokines. This suggests that TLR9 signaling is regulated by the subcellular localization of the receptor.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Bacterias
/
ADN
/
Interferón Tipo I
/
Citocinas
/
Receptor Toll-Like 9
/
Receptores Toll-Like
Idioma:
Coreano
Revista:
Journal of Bacteriology and Virology
Año:
2011
Tipo del documento:
Artículo
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