Stevens-Johnson Syndrome Caused by Influenza Vaccination / 대한피부과학회지

ABSTRACT

Stevens-Johnson syndrome (SJS) is a rare, severe and immune-mediated cutaneous reaction usually secondary to the idiosyncratic reaction of medication, such as sulfonamide, anti-convulsant, NSAIDs and so on. The infection with Mycoplasma pneumoniae is also a well-documented cause. Influenza vaccination is relatively safe and increases with pandemic advance. Mild adverse reactions of influenza vaccination are relatively frequent, such as erythema, pains, fevers, myalgia, headaches and so on. But, severe skin adverse reactions are also very rare. We present a case of seasonal influenza vaccination induced Stevens-Johnson syndrome which has not previously been documented in Korea.