Efficacy of Lactobacillus Acidophilus in Treatment of Acute Diarrhea in Children / 대한소아소화기영양학회지
Korean Journal of Pediatric Gastroenterology and Nutrition
;
: 24-30, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-178366
ABSTRACT
PURPOSE:
Acute diarrhea in young children is a major problem in pediatric hospitals worldwide. We evaluated the clinical efficacy of orally administered Lactobacillus acidophilus in the treatment of acute diarrhea in children.METHODS:
From September 2002 to July 2003 at National Police Hospital 41 children aged 3 months to 5 years with acute diarrhea were enrolled in this study. The patients were randomized to one of two groups to receive either 0.5 x 10(8) colony forming unit (CFU) of L. acidophilus or matching placebo on admission and every 8 hours during hospitalization.RESULTS:
The mean duration of diarrhea in all 41 children was decreased (p=0.001) in the L. acidophilus (40.5 hours) group compared to the placebo (56.6 hours) group. Stool frequency was also reduced (p=0.01) on the 3rd day in the L. acidophilus group. Rotavirus was identified in 58% of the patients. The decrease of duration of diarrhea was more significant in rotavirus-negative patients (p=0.002) compared to the rotavirus-positive patients (p=0.027).CONCLUSION:
L. acidophilus shows to be an effective therapeutic agent in acute diarrhea in children. Further studies are needed to confirm the present findings.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Madre
/
Policia
/
Rotavirus
/
Probióticos
/
Diarrea
/
Hospitalización
/
Hospitales Pediátricos
/
Lactobacillus
/
Lactobacillus acidophilus
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio pronóstico
Límite:
Niño
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Pediatric Gastroenterology and Nutrition
Año:
2004
Tipo del documento:
Artículo
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