Desmoplastic Small Round Cell Tumor of the Sigmoid Colon
Korean Journal of Pathology
;
: 451-454, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-178657
ABSTRACT
Desmoplastic small round cell tumor (DSRCT) is a distinctive disease with a multidirectional differentiation and an aggressive clinical course. It mostly occurs in mesothelial-lined sites, and tumors originating in the paratesticular region, pleura and central nervous system are rarely reported. We report a case of DSRCT occurring in the sigmoid colon of a 39-year-old man, which was difficult to distinguish from small cell neuroendocrine carcinoma. The tumor was characterized by small round cells with irregular nests, cords, or rosette-like structures in the striking desmoplastic stroma. Some tumor cells had a rhabdoid feature with eosinophilic cytoplasmic globules. The tumor cells showed immunoreactivity for cytokeratin, epithelial membrane antigen, vimentin, desmin, neuron-specific enolase and Leu-7. Electron microscopic finding revealed perinuclear globoid whorls of intermediate filaments pushing the nucleus eccentrically.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fosfopiruvato Hidratasa
/
Pleura
/
Sarcoma
/
Colon Sigmoide
/
Huelga de Empleados
/
Vimentina
/
Filamentos Intermedios
/
Sistema Nervioso Central
/
Tumor Rabdoide
/
Colon
Límite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Pathology
Año:
2001
Tipo del documento:
Artículo
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