Antineutrophil cytoplasmic antibody-negative pauci-immune glomerulonephritis with massive intestinal bleeding
Kidney Research and Clinical Practice
;
: 180-184, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-179034
ABSTRACT
A 61-year-old woman was admitted to hospital because of generalized edema and proteinuria. Her renal function deteriorated rapidly. Serum immunoglobulin and complement levels were within normal ranges. An autoantibody examination showed negative for antinuclear antibody and antineutrophil cytoplasmic antibody. Histologic examination of a renal biopsy specimen revealed that all of the glomeruli had severe crescent formations with no immune deposits. The patient was treated with steroid pulse therapy with cyclophosphamide followed by oral prednisolone. Fifteen days later, she experienced massive recurrent hematochezia. Angiography revealed an active contrast extravasation in a branch of the distal ileal artery. We selectively embolized with a permanent embolic agent. On the 45th hospital day, the patient suddenly lost consciousness. Brain computed tomography showed intracerebral hemorrhage. We report a case of antineutrophil cytoplasmic antibody-negative pauci-immune glomerulonephritis with massive intestinal bleeding and cerebral hemorrhage.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Arterias
/
Proteinuria
/
Valores de Referencia
/
Vasculitis
/
Biopsia
/
Encéfalo
/
Proteínas del Sistema Complemento
/
Inmunoglobulinas
/
Prednisolona
/
Angiografía
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Kidney Research and Clinical Practice
Año:
2015
Tipo del documento:
Artículo
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