Incidence, Risk factors, and Clinical Outcomes of Contrast Induced Nephropathy After Percutaneous Coronary Intervention in Elderly Patients
Journal of the Korean Geriatrics Society
;
: 28-34, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-179859
ABSTRACT
BACKGROUND:
Contrast induced nephropathy(CIN) has been known to be a risk factor of significant in-hospital and long-term adverse outcomes. In old aged patients undergoing percutaneous coronary intervention(PCI) in the modern era, the incidence and prognostic implications of nephropathy are unknown.METHODS:
With a retrospective analysis of the clinical and angiographic data, we determined the incidence of, risk factors for, and prognostic implications of CIN(defined as an increase in serum creatinine[Cr] >0.5 mg/dL from baseline) after PCI.RESULTS:
Of 360 patients, 16(4.4%) patients experienced CIN and 5(1.4%) patients required temporary renal replacement therapy (hemodialysis or hemofiltration). Patients with baseline Cr 1.4 mg/dL and diabetic patients had a significant risk of CIN. In multivariate analysis, CIN was significantly associated with baseline renal dysfunction and diabetes showed marginal significance in developing CIN. Twenty-five percent of patients with CINdied during the index hospitalization compared with only 1.2% of patients without CIN (p<0.001). In patients with CIN, events of CIN impair renal function at six-month follow up.CONCLUSIONS:
In old aged patients who are undergoing PCI, diabetic patients with baseline renal impairment are at higher risk for CIN. Furthermore, CIN was highly correlated with death during the index hospitalization.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Incidencia
/
Análisis Multivariante
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Estudios de Seguimiento
/
Angioplastia
/
Terapia de Reemplazo Renal
/
Enfermedad Coronaria
/
Lesión Renal Aguda
/
Intervención Coronaria Percutánea
Tipo de estudio:
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Anciano
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Geriatrics Society
Año:
2004
Tipo del documento:
Artículo
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