Solitary Pigmented Plexiform Neurofibroma in Lower Eyelid: A Case Report
Journal of the Korean Ophthalmological Society
;
: 333-336, 2017.
Artículo
en Coreano
| WPRIM
| ID: wpr-179981
ABSTRACT
PURPOSE:
Solitary plexiform neurofibroma of the eyelid without neurofibromatosis is a rare disease. We report a case of solitary plexiform pigmented neurofibroma of the eyelid without neurofibromatosis. CASESUMMARY:
A 12-year-old male visited our clinic with a painless palpable subcutaneous mass on the right lower eyelid. He had a history of Batter syndrome and attention deficit hyperactivity disorder. On initial presentation, clinical features regarding neurofibromatosis such as Lisch nodule, optic nerve glioma, or high myopia were not observed. We performed excision and biopsy of the lower lid mass under general anesthesia. Macroscopically, the tumor was 4.0 × 1.5 × 1.5 cm in size with irregular nodules. Microscopically, the tumor consisted of multiple, variably sized tortous enlarged nerve fascicles with clusters of pigmented cells. Immunohistochemical results revealed expression of S-100 protein. Pigmented cells express both S-100 and melan-A proteins, while nonpigmented cells express S-100 protein only. The tumor was finally diagnosed as plexiform pigmented neurofibroma. Dermatological evaluation revealed no evidence of systemic neurofibromatosis.CONCLUSIONS:
Plexiform neurofibroma should be considered in the differential diagnosis of an eyelid mass, even if the patient does not have a history or clinical features of neurofibromatosis. Plexiform neurofibroma can be successfully managed with surgical excision.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastorno por Déficit de Atención con Hiperactividad
/
Biopsia
/
Proteínas S100
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Neurofibromatosis 1
/
Neurofibromatosis
/
Neurofibroma Plexiforme
/
Glioma del Nervio Óptico
/
Enfermedades Raras
/
Diagnóstico Diferencial
/
Párpados
Tipo de estudio:
Estudio diagnóstico
Límite:
Niño
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2017
Tipo del documento:
Artículo
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