A Clinical Study of Localized Scleroderma / 대한피부과학회지

ABSTRACT

BACKGROUND: There has been an increase in incidence of localized scleroderma. However observations on the clinical aspects ot localized scleroderma have been scarce in Korea. OBJECTIVE: The purpose of this study was to elucidate the clinical observations and associated diseases of localized scleroderma METHODS: During a 10-year-period from Jan. 1984 to Dec. 1993, 61 patients were evaluated in regard to age incidence, sex ratio, clinical type, location and distribution of plaque and linear type, and associated conditions. RESULTS: l. Age distribution from 4 to 61 years with mean of 27.6 years. Most patients were between 11 to 30 years of age. 2. Sex distribution of male 14 female 47 with 3 1 ratio in favor of female. 3. No difference in right and left involvement. 4. Plaque and linear forms were predominant. 5. The plaque form was distributed evenly while the linear form involved mainly the head and neck. The linear form and generalized form appeared most frequently in developement of associated conditions. 6. ANA test results were positive in 14 patients and most of them were of the speckled pattern. 7. Of the 41 patients who were treated with d-penicillamine, 26 patients showed improvement of their lesions.