Effect of bamboo salt on human gingival fibroblasts / 대한구강보건학회지
Journal of Korean Academy of Oral Health
;
: 90-94, 2014.
Artículo
en Coreano
| WPRIM
| ID: wpr-182190
ABSTRACT
OBJECTIVES:
To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt.METHODS:
Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1beta and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction.RESULTS:
Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1beta secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration.CONCLUSIONS:
The above results suggest that bamboo salt inhibits the release of IL-1beta and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Citocinas
/
Interleucinas
/
Interleucina-6
/
Bahías
/
Reacción en Cadena en Tiempo Real de la Polimerasa
/
Fibroblastos
/
Inflamación
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Academy of Oral Health
Año:
2014
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS