A case of prenatally diagnosed Non-15, Non-22 marker chromosome / 대한산부인과학회지
Korean Journal of Obstetrics and Gynecology
;
: 480-483, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-182324
ABSTRACT
Midtrimester genetic amniocentesis is an important diagnostic tool in prenatal genetic diagnosis and counseling. We can identify karyotypes with metaphase chromosome analysis of cultured amniocytes. Marker chromosomes are defined as unidentified structurally abnormal chromosomes. Incidence of marker chromosomes in the previous reported studies was 0.6-1.5/1,000. They occurred more frequently with advanced maternal age. Ascertainment of chromosomal origin is important because it may be associated with malformation and developmental abnormalities. Recently, identification of the origin and composition of marker chromosomes has been made possible by the use of fluorescent in situ hybridization (FISH). Most marker chromosomes are known to be originated from chromosome 15 or 22, X, Y. We have experienced a case of non-15, non-22 marker chromosome prenatally detected in amniocentesis and FISH, so we reported it with a brief review of literature.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Segundo Trimestre del Embarazo
/
Cromosomas Humanos Par 15
/
Incidencia
/
Edad Materna
/
Hibridación Fluorescente in Situ
/
Consejo
/
Diagnóstico
/
Cariotipo
/
Amniocentesis
/
Metafase
Tipo de estudio:
Estudio diagnóstico
/
Estudio de incidencia
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS