The changes of Corneal Endothelial Morphology after Phacoemulsification by using Healon GV of Viscoat

ABSTRACT

Corneal endothelial cell damage from phacoemulsification has been attributed to mechanical injury caused by surgical manipulation and oxygen free radicals produced by ultrasound. We evaluated role of protective effect in Healon GV and Viscoat on corneal endothelial cell damage during phacoemulsificatin Seventy five eyes underwent phacoemulsigication hrough scleral tunnel incision with posterior chamber lens implantation. Healon GV, 32 eyes and Viscoat, 43 eyes. We analyzed the corneal endothelial morphology using non-contact specualr microscope and analysis program.The percent loss of corneal endothelial density at 3 months postoperative period was greater in Viscoat(5.87%) than in Healon GV(2.47%),although it was not statistically significant(p>0.1). Coefficient of variation in cell size and hexagonality of the corneal endothelial cells also showed no significant difference between the two groups(p>0.1). In conclusion, Healon GV and Viscoat have similar protective effect on the corneal endothelial cell damage induced by ultrasound during phacoemulsification.