The Relationship between the Blood Level of Persistent Organic Pollutants and Common Gastrointestinal Symptoms / 가정의학회지
Korean Journal of Family Medicine
;
: 267-272, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-183287
ABSTRACT
BACKGROUND:
Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to reveal the effects of POPs on the endocrine and nervous system and on cancer, few studies focus on the relationship between low-dose POPs and public health. We attempted to find a relationship between the level of POPs and common gastrointestinal symptoms, including abdominal discomfort, diarrhea, and constipation.METHODS:
We recruited 121 subjects who visited Kyungpook National University Hospital for a health screening. Plasma concentrations were evaluated for 40 kinds of POPs including 17 types of polychlorinated biphenyls and 23 types of organochlorine pesticides. Furthermore, the Korean version of the Rome III criteria was used to identify gastrointestinal symptoms.RESULTS:
Our results showed that abdominal discomfort had an inverse relationship with several polychlorinated biphenyls. Moreover, an inverted U-shaped relationship was observed between abdominal discomfort and several other organochlorine pesticides including p,p'-dichlorodiphenyldichloroethane and p,p'-dichlorodiphenyltrichloroethane, and the effects of these pesticides on abdominal discomfort were similar to that of organochlorine pesticides on obesity and metabolic syndrome.CONCLUSION:
Our results suggest that mild and unspecified gastrointestinal symptoms with no clear cause could be related to POPs levels.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Plaguicidas
/
Plasma
/
Tamizaje Masivo
/
Salud Pública
/
Bifenilos Policlorados
/
Estreñimiento
/
Diarrea
/
Sistema Nervioso
/
Obesidad
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Korean Journal of Family Medicine
Año:
2016
Tipo del documento:
Artículo
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