Psychiatric Disorder in Two Siblings with Hallervorden-Spatz Disease
Psychiatry Investigation
;
: 226-229, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-183811
ABSTRACT
Hallervorden-Spatz disease (HSD) is a rare autosomal-recessive hereditary disorder characterized by the early onset of progressive movement alterations, including dystonia, rigidity, choreoathetosis, and mental deterioration. HSD is also associated with a variety of psychiatric symptoms, primarily depression and mental deterioration. However, psychosis has rarely been reported as a major symptom of HSD. We report two siblings who presented psychiatric symptoms as major clinical presentations, accompanied by ataxic and spastic gait, dysarthria, and typical neuroimaging findings of HSD. A 14-year-old girl presented complex motor tics, stereotypic behavior and anxiety symptoms. Her older brother, a 16-year-old boy, presented prominent auditory hallucinations, persecutory delusions and social withdrawal symptoms. Psychiatric symptoms were improved after atypical antipsychotic treatment. HSD is a rare disease but should be carefully considered in the diagnosis of patients with both motor disorder and various psychiatric symptoms.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ansiedad
/
Trastornos Psicóticos
/
Síndrome de Abstinencia a Sustancias
/
Tics
/
Trastornos Neurológicos de la Marcha
/
Deluciones
/
Enfermedades Raras
/
Hermanos
/
Depresión
/
Disartria
Límite:
Adolescente
/
Humanos
Idioma:
Inglés
Revista:
Psychiatry Investigation
Año:
2009
Tipo del documento:
Artículo
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