Epigenetic Mechanisms of Early Adverse Experience in the Development of Depression / 대한정신약물학회지
Korean Journal of Psychopharmacology
;
: 91-100, 2014.
Artículo
en Coreano
| WPRIM
| ID: wpr-18407
ABSTRACT
Depression is a common mental illness with a high lifetime prevalence rate in the general population. However, the pathophysiology of depression is still poorly understood. Recent studies showed that environmental factors can affect gene expression by modifying epigenetic factors. Early life stress (ELS) is likely a risk factor of lifetime vulnerability to stress and development of depression. ELS or stressful lifetime can induce changes in gene expression through epigenetic mechanism, such as DNA methylation or histone modification. In this article, recent researches on the epigenetic mechanisms of depression will be discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Estrés Psicológico
/
Histonas
/
Expresión Génica
/
Prevalencia
/
Factores de Riesgo
/
Metilación de ADN
/
Depresión
/
Epigenómica
Tipo de estudio:
Estudio de etiología
/
Estudio de prevalencia
/
Factores de riesgo
Idioma:
Coreano
Revista:
Korean Journal of Psychopharmacology
Año:
2014
Tipo del documento:
Artículo
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