Clinical Application of Nutrigenomics
Journal of the Korean Medical Association
;
: 163-172, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-185051
ABSTRACT
Nutritional genomics (nutrigenomics) is the application of high-throughput functional genomics technologies to nutritional science lying in the interface between the nutritional environment and genetic process. It seeks to provide a molecular genetic understanding of how common dietary nutrition affects health by altering the expression or structure of an individual's genetic makeup. On the other hand, nutrigenetics is significantly different from nutrigenomics since nutrigenetics has been used for decades in certain rare monogenic diseases such as phenylketonuria, and has the potential to provide a basis for personalized dietary recommendation based on the individual's specific genetic background in order to prevent common multifactorial disorders decades before their clinical manifestation. The human genome maps and SNP databases, together with the rapid development of tools suitable for investigating genetic and epigenetic changes in small tissue biopsies provide the means to begin the test hypothesis about the mechanisms by which diet influences disease risk including cancer directly in human subjects, could be inevitable flatforms for clinical application to achieve targeted therapy in near future.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenilcetonurias
/
Biopsia
/
Genoma Humano
/
Genoma
/
Genómica
/
Dieta
/
Ciencias de la Nutrición
/
Nutrigenómica
/
Fenómenos Genéticos
/
Epigenómica
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Medical Association
Año:
2006
Tipo del documento:
Artículo
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