Development and Validation of Osteoporosis Risk-Assessment Model for Korean Men
Yonsei Medical Journal
;
: 187-196, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-186105
ABSTRACT
PURPOSE:
The aim of the present study was to develop an osteoporosis risk-assessment model to identify high-risk individuals among Korean men. MATERIALS ANDMETHODS:
The study used data from 1340 and 1110 men > or =50 years who participated in the 2009 and 2010 Korean National Health and Nutrition Examination Survey, respectively, for development and validation of an osteoporosis risk-assessment model. Osteoporosis was defined as T score < or =-2.5 at either the femoral neck or lumbar spine. Performance of the candidate models and the Osteoporosis Self-assessment Tool for Asian (OSTA) was compared with sensitivity, specificity, and area under the receiver operating characteristics curve (AUC). A net reclassification improvement was further calculated to compare the developed Korean Osteoporosis Risk-Assessment Model for Men (KORAM-M) with OSTA.RESULTS:
In the development dataset, the prevalence of osteoporosis was 8.1%. KORAM-M, consisting of age and body weight, had a sensitivity of 90.8%, a specificity of 42.4%, and an AUC of 0.666 with a cut-off score of -9. In the validation dataset, similar results were shown sensitivity 87.9%, specificity 39.7%, and AUC 0.638. Additionally, risk categorization with KORAM-M showed improved reclassification over that of OSTA up to 22.8%.CONCLUSION:
KORAM-M can be simply used as a pre-screening tool to identify candidates for dual energy X-ray absorptiometry tests.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Osteoporosis
/
Densidad Ósea
/
Encuestas Nutricionales
/
Prevalencia
/
Valor Predictivo de las Pruebas
/
Encuestas y Cuestionarios
/
Reproducibilidad de los Resultados
/
Curva ROC
/
Sensibilidad y Especificidad
/
Medición de Riesgo
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2016
Tipo del documento:
Artículo
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