A Case of Ulcerative Colitis with Prolonged Remission Following Azathioprine-Induced Pancytopenia
Intestinal Research
;
: 85-89, 2008.
Artículo
en Coreano
| WPRIM
| ID: wpr-186562
ABSTRACT
Azathioprine (AZA) is widely used for the treatment of inflammatory bowel disease. Bone marrow suppression is a common side effect with AZA treatment. However, data from AZA trials has indicated that a leukocyte count less than 5,000/mm3 was a good predictor of induction and maintenance of remission. Moreover, there is evidence that eradication of sensitized leukocytes by leukapheresis or bone marrow transplantation improves inflammatory bowel disease. We report a case of a patient who had a chronic relapse of ulcerative colitis requiring the frequent use of systemic steroids, but presented prolonged remission following AZA-induced severe pancytopenia. Also colonoscopy showed accelerated healing of diffuse active ulcers following just recovery from pancytopenia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pancitopenia
/
Recurrencia
/
Esteroides
/
Azatioprina
/
Úlcera
/
Médula Ósea
/
Enfermedades Inflamatorias del Intestino
/
Colitis Ulcerosa
/
Colonoscopía
/
Trasplante de Médula Ósea
Límite:
Humanos
Idioma:
Coreano
Revista:
Intestinal Research
Año:
2008
Tipo del documento:
Artículo
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