The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis / 예방의학회지
Journal of Preventive Medicine and Public Health
;
: 349-366, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-187437
ABSTRACT
OBJECTIVES:
We conducted a systematic review and meta-analysis to summarize current evidence regarding the association of parity and duration of breastfeeding with the risk of epithelial ovarian cancer (EOC).METHODS:
A systematic search of relevant studies published by December 31, 2015 was performed in PubMed and EMBASE. A random-effect model was used to obtain the summary relative risks (RRs) and 95% confidence intervals (CIs).RESULTS:
Thirty-two studies had parity categories of 1, 2, and ≥3. The summary RRs for EOC were 0.72 (95% CI, 0.65 to 0.79), 0.57 (95% CI, 0.49 to 0.65), and 0.46 (95% CI, 0.41 to 0.52), respectively. Small to moderate heterogeneity was observed for one birth (p13 months. The summary RRs were 0.79 (95% CI, 0.72 to 0.87), 0.72 (95% CI, 0.64 to 0.81), and 0.67 (95% CI, 0.56 to 0.79), respectively. Only small heterogeneity was observed for <6 months of breastfeeding (p=0.17; Q=18.79, I²=25.5%). Compared to nulliparous women with no history of breastfeeding, the joint effects of two births and <6 months of breastfeeding resulted in a 0.5-fold reduced risk for EOC.CONCLUSIONS:
The first birth and breastfeeding for <6 months were associated with significant reductions in EOC risk.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Ováricas
/
Paridad
/
Reproducción
/
Características de la Población
/
Lactancia Materna
/
Orden de Nacimiento
/
Factores de Riesgo
/
Parto
/
Articulaciones
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
/
Revisiones Sistemáticas Evaluadas
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Journal of Preventive Medicine and Public Health
Año:
2016
Tipo del documento:
Artículo
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