Is Radiotherapy Necessary for Stage 1 Testicular Seminoma? / 대한방사선종양학회지
The Journal of the Korean Society for Therapeutic Radiology and Oncology
;
: 49-54, 2009.
Artículo
en Inglés
| WPRIM
| ID: wpr-188530
ABSTRACT
PURPOSE:
To report on the clinical outcome of patients with stage I testicular seminoma by postoperative radiotherapy (PORT) or surveillance after radical inguinal orchiectomy. MATERIALS ANDMETHODS:
This study is a retrospective review of 32 stage I pure seminoma patients treated between 1996 and 2005 at the Samsung Medical Center. Twenty two of the patients were treated by PORT, which was directed at the paraaortic lymphatics with a median dose of 25.2 Gy in 14 fractions for 3 weeks. The 10 remaining patients were managed by surveillance. The median follow-up period was 96 months with a range of 24 to 155 months.RESULTS:
Clinically, most patients presented with a testicular mass or discomfort. Two of the patients had a history of undescended testes. Pathologically, 23 of the patients had intratubular germ cell neoplasia with seminoma. Both recurrence-free survival (RFS) and overall survival (OS) rates of patients treated by PORT were 100%. In the control group, 1 of the 10 patients suffered a para-aortic lymph node relapse. The RFS and OS rates of the surveillance group were 88.9% and 100%, respectively.CONCLUSION:
No difference in survival was observed between the two groups. Moreover, symptom recurrence was only observed in 1 patient in the control group. The use of PORT may reduce the risk of relapse. With the availability of effective diagnostic and salvage modalities, surveillance monitoring may be considered for patients in good compliance.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recurrencia
/
Orquiectomía
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Seminoma
/
Adaptabilidad
/
Criptorquidismo
/
Células Germinativas
/
Ganglios Linfáticos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
/
Masculino
Idioma:
Inglés
Revista:
The Journal of the Korean Society for Therapeutic Radiology and Oncology
Año:
2009
Tipo del documento:
Artículo
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