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The Adequate Induction Dose of Propofol for Conscious Sedation During Esophagogastroduodenoscopy in Persons 60 Years or Older / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy ; : 134-139, 2010.
Artículo en Coreano | WPRIM | ID: wpr-189263
ABSTRACT
BACKGROUND/

AIMS:

Propofol is an effective sedative drug in endoscopic procedures, but it has potentially serious adverse effects, so close monitoring of the vital signs should be performed during endoscopy. This study was undertaken to determine the adequate induction dose of propofol for safe and effective sedation during esophagogastrodudenoscopy (EGD) in persons 60 years or older.

METHODS:

Three hundred patients who visited our hospital for EGD were randomly assigned to three groups (A,B and C). An initial induction dose of 0.5 mg/kg, 0.75 mg/kg and 1.0 mg/kg of propofol was allocated to groups A, B and C, respectively.

RESULTS:

The 0.5 mg/kg, 0.75 mg/kg and, 1 mg/kg dose of propofol were all safe as an initial dose of propofol for achieving sedation during EGD in persons 60 years or older. There was no difference in the total amount of propofol among the three groups. Group C had a significantly shorter induction time and a lower dose was required for an additional injection of propofol without increasing adverse events, as compared to the two other groups.

CONCLUSIONS:

We suggest that 1 mg/kg of propofol is an effective induction dose for sedation during EGD in persons 60 years or older.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Propofol / Sedación Consciente / Endoscopía del Sistema Digestivo / Endoscopía / Signos Vitales Límite: Anciano / Humanos Idioma: Coreano Revista: Korean Journal of Gastrointestinal Endoscopy Año: 2010 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Propofol / Sedación Consciente / Endoscopía del Sistema Digestivo / Endoscopía / Signos Vitales Límite: Anciano / Humanos Idioma: Coreano Revista: Korean Journal of Gastrointestinal Endoscopy Año: 2010 Tipo del documento: Artículo