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Asthma Severity and the Controller Prescription in Children at 12 Tertiary Hospitals
Allergy, Asthma & Immunology Research ; : 52-60, 2017.
Artículo en Inglés | WPRIM | ID: wpr-189584
ABSTRACT

PURPOSE:

Guidelines need to be tailored to where they are applied. We aimed to describe the distinctive asthma severity profile and the pattern of controller prescription in Korean children.

METHODS:

Twelve pediatric allergists from tertiary medical centers reviewed medical records of all asthmatic children who visited their clinics between September 1 and November 30 of 2013. Controller prescriptions were re-classified into 4 categories, then the prevalence of each asthma severity category and the controller prescription patterns according to asthma severity assessed by a Western (Global Initiative for Asthma, GINA) and an Asia-Pacific (Japanese Pediatric GuideLine, JPGL) guideline were evaluated.

RESULTS:

A total of 840 cases were reviewed. Both GINA and JPGL revealed that 328 (39.0%) and 249 (29.6%) subjects had intermittent asthma whereas 24 (2.9%) and 21 (2.5%) subjects had severe persistent asthma, respectively. Although higher category controllers tended to be prescribed to those who had more severe asthma, there was much overlap in categories of prescribed controllers between groups with regard to asthma severities. Leukotriene receptor antagonists (LTRA) was the most frequently prescribed as a single controller (40%) or as an add-on medication (19%) in the group of asthmatic children <6 years.

CONCLUSIONS:

Korean children have distinctive patterns of asthma severity and management strategies with a lower prevalence of severe asthma and a preference toward LTRA rather than low dose inhaled corticosteroids (ICS) alone or add-on long-acting beta-agonist (LABA) in the group of <6 year-old asthmatics that has not been predicted in Western countries. Thus, strategies tailored to regional situations need to be developed and recommended.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Asma / Registros Médicos / Prevalencia / Corticoesteroides / Antagonistas de Leucotrieno / Prescripciones / República de Corea / Centros de Atención Terciaria Tipo de estudio: Guía de Práctica Clínica / Estudio de prevalencia / Estudio pronóstico Límite: Niño / Humanos País/Región como asunto: Asia Idioma: Inglés Revista: Allergy, Asthma & Immunology Research Año: 2017 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Asma / Registros Médicos / Prevalencia / Corticoesteroides / Antagonistas de Leucotrieno / Prescripciones / República de Corea / Centros de Atención Terciaria Tipo de estudio: Guía de Práctica Clínica / Estudio de prevalencia / Estudio pronóstico Límite: Niño / Humanos País/Región como asunto: Asia Idioma: Inglés Revista: Allergy, Asthma & Immunology Research Año: 2017 Tipo del documento: Artículo