Working Memory Deficits in Ultra-High Risk for Psychosis and Schizophrenia / 대한정신분열병학회지
Korean Journal of Schizophrenia Research
;
: 66-72, 2012.
Artículo
en Coreano
| WPRIM
| ID: wpr-191081
ABSTRACT
OBJECTIVES:
The aim of this study was to investigate whether verbal and spatial working memory functions were impaired not only in patients with schizophrenia but also in people at ultra-high risk for first-episode psychosis.METHODS:
Twenty-five patients (M 13, F 12) with schizophrenia (SPR), 21 people at ultra-high risk for psychosis (UHR)(M 10, F 11) and 19 normal controls (NC)(M 10, F 9) were recruited. The working memory was assessed by using the verbal and spatial n-back test. The working memory load increased incrementally from the 0-back to the 3-back condition.RESULTS:
SPR performed significantly lower than NC and UHR in terms of hit rates of verbal and spatial n-back test. UHR subjects conducted significantly lower than NC and higher in trend-level than SPR in terms of hit rates of verbal and spatial n-back test. These differences were derived from the high working memory load (2-back and 3-back), not from the low working memory load (0-back and 1-back). There was no significant difference between the verbal and spatial n-back test across the three groups.CONCLUSION:
These findings suggest that verbal and spatial working memory dysfunction may be general rather than differential in terms of stimuli modality, and this working memory deficit may be an important trait factor in schizophrenia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastornos Psicóticos
/
Esquizofrenia
/
Memoria a Corto Plazo
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Schizophrenia Research
Año:
2012
Tipo del documento:
Artículo
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