Evaluation of the MicroScan MICroSTREP Plus Antimicrobial Panel for Testing beta-Hemolytic Streptococci and Viridans Group Streptococci / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 185-190, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-193619
ABSTRACT
BACKGROUND:
In order to determine the clinical usefulness of the MicroScan (Siemens Healthcare Diagnostics, USA) MICroSTREP plus antimicrobial panel (MICroSTREP) for testing antimicrobial susceptibility of beta-hemolytic streptococci (BHS) and viridans group streptococci (VGS), we compared the accuracy of MICroSTREP with that of the CLSI reference method.METHODS:
Seventy-five BHS and 59 VGS isolates were tested for antimicrobial susceptibility to ampicillin, penicillin, cefotaxime, meropenem, erythromycin, clindamycin, levofloxacin, and vancomycin by using MICroSTREP and the CLSI agar dilution method.RESULTS:
The overall essential agreement with regard to minimum inhibitory concentrations (MICs) (within +/-1 double dilution) between MICroSTREP and the CLSI reference method was 98.2%, and categorical agreement (CA) was 96.9%. For the BHS isolates, the CA for erythromycin was 96.0%, whereas that for cefotaxime, meropenem, levofloxacin, and vancomycin (for ampicillin, penicillin, and clindamycin; 98.7%) was 100%. For the VGS isolates, the CA for penicillin was 84.7% and that for erythromycin, clindamycin, and vancomycin (for meropenem, 86.5%; for ampicillin, 88.1%; and for cefotaxime and levofloxacin, 96.6%) was 100%. All categorical errors of penicillin and ampicillin in the VGS isolates were minor.CONCLUSIONS:
The accuracy of MICroSTREP is comparable to that of the CLSI reference method, suggesting that this panel can be effective for testing antimicrobial susceptibility of BHS and VGS.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Juego de Reactivos para Diagnóstico
/
Infecciones Estreptocócicas
/
Streptococcus
/
Pruebas de Sensibilidad Microbiana
/
Farmacorresistencia Bacteriana
/
Estreptococos Viridans
/
Antibacterianos
Límite:
Humanos
Idioma:
Inglés
Revista:
The Korean Journal of Laboratory Medicine
Año:
2011
Tipo del documento:
Artículo
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