A Case of Band Heterotopia with Lennox-Gastaut Syndrome / 대한소아신경학회지
Journal of the Korean Child Neurology Society
;
(4): 348-353, 1999.
Artículo
en Coreano
| WPRIM
| ID: wpr-194155
ABSTRACT
Band heterotopia is a rare neuronal migration disorder, resulting in epilepsy and mental retardation. Epilepsy in band heteropopia, of which Lennox-Gastaut syndrome constituted about 20%, varied in nature and degree of severity. Band heterotopia can be diagnosed by brain magnetic resonance imaging (MRI), showing another diffuse layer of gray matter underlying the normal-looking cortex with intervening thin rim of white matter. While positron emission tomography (PET) with [18F]-fluorodeoxyglucose revealed glucose uptake similar to the overlying cortex, single photon emission computerized tomography (SPECT) findings of band heterotopia have not been reported. We report a 8-year-old girl who presented with variable types of generalized seizures and mild mental retardation. She was diagnosed as having band heterotopia with Lennox-Gastaut syndrome by MRI and interictal electroencephalogram (EEG) showing immature background and generalized 2 Hz slow spike and wave complexes. Interictal SPECT, using Tc 99m hexamethyl propylenamine oxime (Tc 99m-HMPAO), revealed the same degree of perfusion in both the areas of band heterotopia and the overlying cortex. By using valproate and lamotrigine, she is now in stable condition with a significant decrease in seizure frequency.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Perfusión
/
Convulsiones
/
Encéfalo
/
Imagen por Resonancia Magnética
/
Tomografía Computarizada de Emisión de Fotón Único
/
Ácido Valproico
/
Tomografía de Emisión de Positrones
/
Electroencefalografía
/
Epilepsia
/
Malformaciones del Desarrollo Cortical del Grupo II
Límite:
Niño
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Child Neurology Society
Año:
1999
Tipo del documento:
Artículo
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