Development of Clinical Data Mart of HMG-CoA Reductase Inhibitor for Varied Clinical Research
Endocrinology and Metabolism
;
: 90-98, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-194425
ABSTRACT
BACKGROUND:
The increasing use of electronic medical record (EMR) systems for documenting clinical medical data has led to EMR data being increasingly accessed for clinical trials. In this study, a database of patients who were prescribed statins for the first time was developed using EMR data. A clinical data mart (CDM) was developed for cohort study researchers.METHODS:
Seoul St. Mary's Hospital implemented a clinical data warehouse (CDW) of data for ~2.8 million patients, 47 million prescription events, and laboratory results for 150 million cases. We developed a research database from a subset of the data on the basis of a study protocol. Data for patients who were prescribed a statin for the first time (between the period from January 1, 2009 to December 31, 2015), including personal data, laboratory data, diagnoses, and medications, were extracted.RESULTS:
We extracted initial clinical data of statin from a CDW that was established to support clinical studies; the data was refined through a data quality management process. Data for 21,368 patients who were prescribed statins for the first time were extracted. We extracted data every 3 months for a period of 1 year. A total of 17 different statins were extracted. It was found that statins were first prescribed by the endocrinology department in most cases (69%, 14,865/21,368).CONCLUSION:
Study researchers can use our CDM for statins. Our EMR data for statins is useful for investigating the effectiveness of treatments and exploring new information on statins. Using EMR is advantageous for compiling an adequate study cohort in a short period.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oxidorreductasas
/
Estudios de Cohortes
/
Inhibidores de Hidroximetilglutaril-CoA Reductasas
/
Diagnóstico
/
Endocrinología
/
Prescripciones
/
Registros Electrónicos de Salud
/
Seúl
/
Exactitud de los Datos
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio de incidencia
/
Estudio observacional
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Endocrinology and Metabolism
Año:
2017
Tipo del documento:
Artículo
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