Inflammation and Hepatic Fibrosis, Then Hepatocellular Carcinoma / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 320-324, 2015.
Artículo
en Coreano
| WPRIM
| ID: wpr-195648
ABSTRACT
Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and cirrhosis develops in patients with chronic liver inflammation. Therefore, there is no doubt that there exist some strong connection among inflammation, fibrosis, and cancer. In fact, chronic unresolved inflammation is associated with persistent hepatic injury and concurrent regeneration, leading to sequential development of fibrosis, cirrhosis, and eventually HCC. This review will discuss the common mechanism of inflammation and fibrosis in chronic liver diseases, and then demonstrate why HCC develops in inflammatory and fibrotic conditions.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Lipopolisacáridos
/
Carcinoma Hepatocelular
/
Receptores Toll-Like
/
Bacterias Gramnegativas
/
Hepatitis Crónica
/
Inflamación
/
Hígado
/
Cirrosis Hepática
/
Neoplasias Hepáticas
/
Hipoxia
Límite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Año:
2015
Tipo del documento:
Artículo
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