Clinical Characteristics of Symptomatic Clostridium difficile Infection in Children: Conditions as Infection Risks and Whether Probiotics Is Effective / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition
;
: 232-238, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-195964
ABSTRACT
PURPOSE:
This study investigated the clinical presentations of symptomatic Clostridium difficile infection (CDI) in children.METHODS:
We reviewed the medical records of 43 children aged 3 days, and the most frequently prescribed antibiotic was amoxicillin-clavulanate (35.7%). Twenty-eight patients were diagnosed with CDI despite taking probiotic supplements, most commonly Lactobacillus acidophilus (53.6%). The most common symptom was diarrhea (72.1%) at the time CDI was diagnosed. C. difficile was eradicated in 11 patients (25.6%) after treatment with oral metronidazole for 10-14 days, and in the two patients (4.6%) who required two courses of oral metronidazole. Sixteen patients (37.2%) showed clinical improvement without any treatment.CONCLUSION:
This study showed the various clinical characteristics of CDI in children and that preexisting clinical conditions favored the development of CDI. In addition, CDI was found to occur in a number of patients even after probiotic prophylaxis given in conjunction with antibiotic therapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Registros Médicos
/
Factores de Riesgo
/
Clostridioides difficile
/
Probióticos
/
Diarrea
/
Enfermedades Gastrointestinales
/
Lactobacillus acidophilus
/
Metronidazol
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Factores de riesgo
Límite:
Niño
/
Humanos
Idioma:
Inglés
Revista:
Pediatric Gastroenterology, Hepatology & Nutrition
Año:
2014
Tipo del documento:
Artículo
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