Paracentric Inversions Found in Prenatal Diagnosis
Journal of Genetic Medicine
;
: 104-108, 2013.
Artículo
en Inglés
| WPRIM
| ID: wpr-196055
ABSTRACT
PURPOSE:
This study was designed to confirm whether the paracentric inversions of fetuses and parents may be harmless. MATERIALS ANDMETHODS:
We report 10 cases (0.14%) with paracentric inversions among 7,181 prenatal cases observed during prenatal diagnosis performed at Cheil General Hospital between January 2009 and June 2013. We used cytogenetic GTL- and RBG-banding techniques.RESULTS:
Of the 10 cases, nine cases were transmitted from each of the parents, and one case was de novo. Nine cases were phenotypically normal up to one month of age after birth. One case was lost to follow-up. We present prenatal diagnosis and follow-up examination of the fetuses with paracentric inversion.CONCLUSION:
Based on our cases, most paracentric inversions are considered to be harmless. The precise identification of paracentric inversions might be clinically important and helpful for genetic counseling.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Padres
/
Diagnóstico Prenatal
/
Muestra de la Vellosidad Coriónica
/
Estudios de Seguimiento
/
Citogenética
/
Parto
/
Perdida de Seguimiento
/
Feto
/
Asesoramiento Genético
/
Amniocentesis
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Inglés
Revista:
Journal of Genetic Medicine
Año:
2013
Tipo del documento:
Artículo
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