Cytomegalovirus as a Cause of Recurrent Anterior Uveitis in Immunocompetent Patients
Journal of the Korean Ophthalmological Society
;
: 1245-1249, 2010.
Artículo
en Coreano
| WPRIM
| ID: wpr-196923
ABSTRACT
PURPOSE:
This study aimed to identify various infectious causes in unilateral recurrent hypertensive anterior uveitis in immunocompetent individuals.METHODS:
Twenty eyes of 20 patients diagnosed with recurrent hypertensive anterior uveitis, who had negative systemic uveitis lab results, were enrolled. Polymerase chain reaction (PCR) was performed in the aqueous humor and peripheral blood specimens to detect the following infectious agents cytomegalovirus (CMV), herpes simplex virus-1 (HSV-1), varicella zoster virus (VZV), toxoplasma.RESULTS:
The mean age of 20 patients was 41.8 +/- 15.9 year (19-77 year), and 14 (70%) patients were male. CMV was positive in 7 eyes (35%) and was detected only in aqueous humor. HSV-1 was positive in 5 (25%) eyes; only in aqueous humor in 2 eyes, only in blood in 1 eye, and in both specimens in 2 eyes. Only 1 (5%) eye was positive for toxoplasma in the aqueous humor.CONCLUSIONS:
This study demonstrated that CMV might be another major infectious cause in recurrent hypertensive anterior uveitis in immunocompetent patients. If CMV is detected, it might be reasonable to add appropriate antiviral agents, rather than treating only with immunosuppresive and hypotensive drugs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Antivirales
/
Humor Acuoso
/
Poliestirenos
/
Piridinas
/
Tiazoles
/
Toxoplasma
/
Uveítis
/
Uveítis Anterior
/
Reacción en Cadena de la Polimerasa
/
Herpesvirus Humano 1
Límite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2010
Tipo del documento:
Artículo
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