Chronic urticaria treated with tacrolimus

ABSTRACT

Cyclosporine is a calcineurin inhibitor which is used to treat antihistamine-resistant chronic urticaria. Unfortunately, some patients cannot use cyclosporine due to its side effects. Tacrolimus is another calcineurin inhibitor with a slightly different side effect profile from that of cyclosporine, and a few cases of chronic urticaria have been treated with tacrolimus. Here, we report a patient with anti-histamine-resistant chronic urticaria, who could not be treated with cyclosporine, due to side effects, but was controlled successfully with tacrolimus. To the best of our knowledge, this is the first report of tacrolimus-treated chronic urticaria in Korea.