A Discrepancy between (131)I-Metaiodobenzylguanidine ((131)I-MIBG) Scintigraphy and (18)F-FDG PET/CT after (131)I-MIBG Therapy in a Patient with Recurred Malignant Pheochromocytoma / 핵의학분자영상

ABSTRACT

A 59-year-old woman who was diagnosed with malignant pheochromocytoma underwent (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT). She had undergone left adrenalectomy for pheochromocytoma 4 years previously. Recent multiple metastatic pulmonary nodules were noted on the chest X-ray. After treatment with (131)I-metaiodobenzylguanidine ((131)I-MIBG) with 7.4 GBq, post-therapy (131)I-MIBG scintigraphy depicted multiple distant metastases including lung, liver, abdominal para-aortic and mesenteric lymph nodes. (18)F-FDG PET/CT also depicted multiple metastases in lung, liver, and abdominal para-aortic lymph nodes, but some lesions were not shown. In this case, (131)I-MIBG scintigraphy found additional lesions in metastatic malignant pheochromocytoma.