Treatment of Intravenous Immune-Globulin Resistant Kawasaki Disease with Corticosteroids
Journal of the Korean Pediatric Society
;
: 1453-1457, 1997.
Artículo
en Coreano
| WPRIM
| ID: wpr-198908
ABSTRACT
PURPOSE:
To evaluate the efficacy of steroid therapy on prevention of development and progression of coronary artery aneurysm in intravenous immune globulin (IVIG)-resistant Kawasaki disease, we treated three children with high dose of intravenous methylprednisolone followed by low dose oral prednisolone.METHODS:
We selected three children with Kawasaki disease who did not repond or who initially responded but soon developed recrudescent fever after retreatment of IVIG (total 4gm/kg). These three patients were treated with high dose methylprednisolone (10mg/kg) intravenously and followed by low dose prednisolone (1mg/kg) orally for 7 days. Echocardiographic evalutions were performed within 8 days of admission (before steroid therapy), at discharge and 1 month after discharge.RESULTS:
All three patients showed rapid normalization of clinical symptoms and did not developed significant coronry artery abnormalities. No adverse reaction was observed.CONCLUSIONS:
Steroid therapy (mini pulse methylprednisolone and prednisolone therapy) is valuable for patients with Kawasaki disease resistant to intravenous immune globulin therapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Arterias
/
Metilprednisolona
/
Prednisolona
/
Ecocardiografía
/
Inmunoglobulinas Intravenosas
/
Corticoesteroides
/
Retratamiento
/
Vasos Coronarios
/
Fiebre
/
Aneurisma
Límite:
Niño
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Pediatric Society
Año:
1997
Tipo del documento:
Artículo
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