One-month Serum Creatinine Level is the IndePendent Predictor of Long Term Graft Function Following Renal Transplant / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 94-97, 2007.
Artículo
en Coreano
| WPRIM
| ID: wpr-199121
ABSTRACT
PURPOSE:
The current organ shortage in renal transplantation underscores the importance of optimizing long- term graft survival. Despite the significant improvement in the results of renal transplantation since the introduction of cyclosporine, graft loss after fist year of transplantation remains a significant and unresolved problem. This study showed renal function at 1 month after transplantation as a prognostic factor influencing long-term renal graft survival.METHODS:
The results of 683 cases of renal transplantations performed from 1978 to 2001 in our center were analysed. We divided into 3 groups according to the serum creatinine level (group 1 60), donor sex, donor type (related, unrelated, cadevaric), recipient age (60), recipient sex, HLA matching, acute rejection, delayed graft function were also analysed.RESULTS:
The acute rejection rates in each group were 17.1%, 40.6%, 71.7% retrospectively (P=0.000). The frequencies of delayed graft function were 3.9%, 9.0%, 36.2% retrospectively (P=0.000). There was significant difference of graft survival between each group (P=0.000). In addition, graft survival in group with acute rejection showed significant difference according to creatinine level at 1 month.CONCLUSION:
We can predict long-term graft survival and early renal function through serum creatinine levels after transplantation. Therefore, serum creatinine level at first month of transplantation was prognostic factor in predicting long-term graft survival.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Donantes de Tejidos
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Trasplante de Riñón
/
Ciclosporina
/
Trasplantes
/
Creatinina
/
Funcionamiento Retardado del Injerto
/
Supervivencia de Injerto
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Coreano
Revista:
The Journal of the Korean Society for Transplantation
Año:
2007
Tipo del documento:
Artículo
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