Initial Response to Treatment was Highly Associated with the Prognosis of Childhood Rhabdomyosarcoma: A Retrospective Analysis of a Single Center Experience in Korea / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 111-115, 2008.
Artículo
en Inglés
| WPRIM
| ID: wpr-199994
ABSTRACT
PURPOSE:
Following the introduction of a multimodal approach to diagnosis and treatment, the prognosis of rhabdomyosarcoma (RMS) has markedly improved over the last three decades. However, there are few data on treatment outcomes in Korean patients. MATERIALS ANDMETHODS:
We performed a retrospective analysis of 77 patients with RMS diagnosed and treated at Seoul National University Children's Hospital between 1986 and 2005.RESULTS:
The overall 5-year survival and event-free survival rates for all patients were 77% and 59%, respectively. The Intergroup Rhabdomyosarcoma Study clinical grouping and initial response to treatment (20-week response) were important prognostic factors.CONCLUSIONS:
The outcome of childhood RMS was closely associated with the initial staging and the initial response to treatment. Modulating therapies according to initial responses and risk factors is critical, and new treatment strategies for high-risk patients are needed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Rabdomiosarcoma
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Supervivencia sin Enfermedad
/
Corea (Geográfico)
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Niño
/
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Cancer Research and Treatment
Año:
2008
Tipo del documento:
Artículo
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