Sulpiride in Meige's Syndrome: Possible Role of Glutamate
Yonsei Medical Journal
;
: 62-65, 1988.
Artículo
en Inglés
| WPRIM
| ID: wpr-20076
ABSTRACT
Sulpiride, a selective antagonist for adenylate cyclase-independent dopamine receptors, was administrated to 25 patients with blepharospasm and oromandibular dystonia(Meige's syndrome). Of the 25, 7 patients (28%) exhibited marked and lasting improvement with sulpiride and 12 patients (48%) showed mild or transient improvement. This favorable therapeutic response to sulpiride suggests that striatal glutamate underactivity may play a role in the pathophysiology of Meige's syndrome as a primary or secondary defect.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Sulpirida
/
Enfermedades de los Ganglios Basales
/
Dopamina
/
Ácido Glutámico
/
Cuerpo Estriado
/
Glutamatos
/
Síndrome de Meige
/
Persona de Mediana Edad
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
1988
Tipo del documento:
Artículo
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