RNA polymerase II carboxy-terminal domain with multiple connections
Experimental & Molecular Medicine
;
: 247-254, 2007.
Artículo
en Inglés
| WPRIM
| ID: wpr-201430
ABSTRACT
The largest subunit of eukaryotic RNA polymerase II contains a unique domain at its carboxy-terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of an evolutionarily conserved heptapeptide repeat (YSPTSPS). Over the past decade, there has been increasing attention on the role of the CTD in transcription regulation in the view of mRNA processing and chromatin remodeling. This paper provides a brief overview of the recent progress in the dynamic changes in CTD phosphorylation and its role in integrating multiple nuclear events.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fosforilación
/
Transcripción Genética
/
ARN Polimerasa II
/
ARN Mensajero
/
Cromatina
/
Histonas
/
Secuencia de Aminoácidos
/
Estructura Terciaria de Proteína
/
Secuencia Conservada
/
Secuencias de Aminoácidos
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Experimental & Molecular Medicine
Año:
2007
Tipo del documento:
Artículo
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