Functions of PIWI proteins in spermatogenesis / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 61-67, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-202789
ABSTRACT
Recently, a significant understanding of the molecular mechanisms regulating spermatogenesis has been achieved utilizing small RNA molecules (small RNAs), including small interfering RNAs (siRNAs), microRNAs (miRNAs), and Piwi-interacting RNAs (piRNAs) which emerged as important regulators of gene expression at the post-transcriptional or translation level. piRNAs are only present in pachytene spermatocytes and round spermatids, whereas miRNAs are expressed abundantly in male germ cells throughout spermatogenesis. This review is aimed at providing a glimpse of piRNAs and their interacting family proteins such as PIWIL1, PIWIL2, and PIWIL4 in spermatogenesis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Espermátides
/
Espermatocitos
/
Espermatogénesis
/
ARN
/
Proteínas
/
Expresión Génica
/
MicroARNs
/
ARN Interferente Pequeño
/
Células Germinativas
/
Infertilidad
Límite:
Animales
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Clinical and Experimental Reproductive Medicine
Año:
2011
Tipo del documento:
Artículo
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