Ebola outbreak in Western Africa 2014: what is going on with Ebola virus?
Clinical and Experimental Vaccine Research
;
: 17-22, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-203154
ABSTRACT
The 2014 outbreak of Ebola virus disease (EVD) in West Africa, caused by Ebola virus (Zaire Ebola virus species), is the largest outbreak of EVD in history. It cause hemorrhagic fever in human and nonhuman primates with high mortality rate up to 90% and can be transmitted by direct contact with blood, body fluids, skin of EVD patients or persons who have died of EVD. As of December 17, 2014, 450 healthcare personnel are known to have been infected with Ebola, of whom 244 died. For development of Ebola vaccine and treatment are highly difficult due to its dangerous and accessibility that requires biosafety level 4 (BSL-4) to conduct experiment. Also there is no specific vaccine and treatment for Ebola virus; however, many candidate vaccines and antiviral-drugs such as ZMapp and TKM-Ebola are being developed for Ebola virus disease. In this review, we focus on the epidemiology of 2014 outbreak of Ebola virus and candidate agent for preventing and curing from Ebola virus.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Primates
/
Piel
/
Líquidos Corporales
/
Vacunas
/
Epidemiología
/
Mortalidad
/
Fiebre Hemorrágica Ebola
/
África Occidental
/
Atención a la Salud
/
Ebolavirus
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
País/Región como asunto:
Africa
Idioma:
Inglés
Revista:
Clinical and Experimental Vaccine Research
Año:
2015
Tipo del documento:
Artículo
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