The Clinicopathologic Study of Granuloma Annulare / 대한피부과학회지

ABSTRACT

BACKGROUND: Granuloma annulare is a chronic inflammatory condition of unknown cause. There are only two clinicopathologic studies in Korea. OBJECTIVES: Our purpose was to investigate the clinicopathologic findings of granuloma annulare and literature review. METHODS: Twenty two biopsy-proved cases of granuloma annulare were reviewed. We examined their clinical and pathological findings. RESULTS: The incidence showed a peak under 20 years old(59.1%) and females affected twice as much as males. Average onset years was 21.5 years old and mean disease duration was 20 months. The lesions were located almost in dermis(77.2%) and interstitial infiltration type was most common. CONCLUSION:There were no large epidemiologic difference from previously reported studies. Granuloma annulare is not an uncommon disease. It is important to distinguish granuloma annulare from many other mucin producing, granuloma forming diseases.