Cutaneous Rosai-Dorfman Disease (RDD) Mimicking Primary Cutaneous Marginal Zone B-cell Lymphoma / 대한피부과학회지
Korean Journal of Dermatology
; : 809-813, 2013.
Article
en Ko
| WPRIM
| ID: wpr-204072
Biblioteca responsable:
WPRO
ABSTRACT
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is an idiopathic, benign, histiocytic proliferative disease involving lymph nodes and extranodal sites. A 52-year-old woman presented with a 2-year history of multiple non-tender, erythematous nodules on her face. The initial punch biopsy showed lymphoid follicle-like aggregation of CD20 positive lymphocytes in the papillary dermis consisting of primary cutaneous marginal zone B-cell lymphoma. She underwent a 3-month course of radiotherapy, but the lesions progressed. The re-biopsy specimen revealed marked histiocytes with positive CD68 and S-100 proteins. The patient was treated with prednisolone and isotretinoin to which she responded slightly. Repeated histopathologic examinations enable us to make a definite diagnosis. Differentiating these two disorders as early as possible is crucial for appropriate treatment.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Radioterapia
/
Biopsia
/
Prednisolona
/
Linfocitos
/
Isotretinoína
/
Proteínas S100
/
Histiocitosis Sinusal
/
Linfoma de Células B de la Zona Marginal
/
Dermis
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Diagnóstico
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Año:
2013
Tipo del documento:
Article