Comparative Study of 20% Aluminum Chloride Solution and Botulinum Toxin A Injection in the Treatment of Patients with Primary Palmar Hyperhidrosis / 대한피부과학회지
Korean Journal of Dermatology
; : 334-340, 2008.
Article
en Ko
| WPRIM
| ID: wpr-204120
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: Primary hyperhidrosis carries a substantial psychological and social burden. Early detection and management can significantly improve a patient's quality of life. A large number of therapeutic options are used, such as the application of topical agents, iontophoresis, sympathectomy, and botulinum toxin injection. OBJECTIVE: We aim to comprehensively evaluate the effects of botulinum toxin type A and 20% aluminum chloride on primary palmar hyperhidrosis. METHODS: A total of 55 patients with clinical diagnosis of primary hyperhidrosis were treated by botulinum toxin type A and 20% aluminum chloride solution. To prospectively assess the effects on primary palmar hyperhidrosis, we checked corneometer at baseline, 2 and 4 months later. By regular meetings with patients, including telephone interviews, we analyzed patients' subjective satisfaction scores and complaints during the follow=up periods. RESULTS: During the 2-month period, as compared with that of the control group, the level of corneometer of both groups declined. In the 4-month period, the group treated with 20% aluminum chloride sustained a lower level of corneometer. In the questionnaire, in the 2-month period, the group treated with botulinum toxin resulted in a lower level of overall treatment scores than that of the group treated with 20% aluminum chloride. However, in the 4-month period, the group treated with aluminum chloride showed lower scores. CONCLUSION: Both botulinum toxin type A and aluminum chloride solution were safe and well tolerated, producing high levels of patient satisfaction. However, considering the long-term efficacy of treatment, aluminum chloride may be a more suitable mode of treatment for primary palmar hyperhidrosis.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Calidad de Vida
/
Simpatectomía
/
Toxinas Botulínicas
/
Cloruros
/
Iontoforesis
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Entrevistas como Asunto
/
Estudios Prospectivos
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Encuestas y Cuestionarios
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Satisfacción del Paciente
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Compuestos de Aluminio
Tipo de estudio:
Observational_studies
/
Qualitative_research
/
Screening_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Año:
2008
Tipo del documento:
Article