Factors Associated with Airway Disease and Interstitial Lung Disease in Rheumatoid Arthritis
Journal of Rheumatic Diseases
;
: 101-108, 2016.
Artículo
en Coreano
| WPRIM
| ID: wpr-205475
ABSTRACT
OBJECTIVE:
This study examined lung involvement in patients with rheumatoid arthritis (RA) and identified factors associated with airway disease (AD) and interstitial lung disease (ILD).METHODS:
A total of 507 RA patients were enrolled in a cross-sectional study. Lung involvement was assessed by high-resolution computed tomography scan. The patient groups were classified according to normal, AD, and ILD. Multinomial logistic regression analysis was performed to identify factors associated with AD and ILD.RESULTS:
The most frequent lung involvement was AD (38.3%) followed by ILD (12.6%). Old age (adjust odds ratio [aOR] 2.58, 95% confidence interval [CI] 1.70 to 3.90 for AD; aOR 4.38, 95% CI 2.30 to 8.35 for ILD), male gender (aOR 2.57, 95% CI 1.22 to 5.42 for AD; aOR 5.48, 95% CI 2.20 to 13.65 for ILD) were factors associated with AD and ILD in RA patients. ILD was associated with short disease duration (aOR 0.30, 95% CI 0.14 to 0.62), AD was associated with high titers of anti-cyclic citrullinated peptides antibodies (anti-CCP; aOR 1.61, 95% CI 1.07 to 2.44).CONCLUSION:
AD was the most frequent lung involvement in patients with RA. Old age and male gender were both associated with AD and ILD. Short disease duration was associated with ILD. High titers of anti-CCP was associated with AD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Péptidos
/
Artritis Reumatoide
/
Tomografía Computarizada por Rayos X
/
Modelos Logísticos
/
Oportunidad Relativa
/
Estudios Transversales
/
Factores de Riesgo
/
Enfermedades Pulmonares Intersticiales
/
Pulmón
/
Enfermedades Pulmonares Obstructivas
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of Rheumatic Diseases
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS