Micrographia after Midbrain Tegmental Infarction

ABSTRACT

Micrographia is an abnormal reduction in writing size that is a specific behavioral deficit associated with Parkinson's disease. A 24-year-old right-handed woman presented with sudden-onset right-hand micrographia. Brain magnetic resonance imaging revealed an infarction of the right tegmentum of the lower midbrain. The mechanism of micrographia caused by pure midbrain tegmental infarction remains unclear. This case could provide evidence of the functional anatomy of a direct connection between the cerebellum and basal ganglia through the midbrain.